Photo: Harry How / Getty Images Sport / Getty Images
The Cleveland Cavaliers are 4.5-point favorites for a decisive Game 6 of the second round of the NBA Playoffs against the Detroit Pistons at Rocket Arena on Friday, tipping off at 7 p.m. ET on Amazon Prime Video. The Cavaliers have a 3-2 series lead.
Watch the NBA, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up.
Listen to the game on Newsradio WTAM 1100
Pistons vs. Cavaliers Predictions for Friday
Our computer projection model for this contest predicts a final tally of Pistons 115, Cavaliers 114.
- Moneyline Pick: Pistons (+149)
- Total Pick: Over 210.5 (computer predicts 228.9 points)
- Pick ATS: Pistons (+4.5)
- More NBA PredictionsSpurs vs. Timberwolves Predictions
Recent Pistons vs. Cavaliers Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 5/13/2026 | Pistons | -4.5 | 210.5 | -173 | +146 | 117-113 CLE |
| 5/11/2026 | Cavaliers | -3.5 | 212.5 | -163 | +137 | 112-103 CLE |
| 5/9/2026 | Cavaliers | -4.5 | 211.5 | -191 | +160 | 116-109 CLE |
| 5/7/2026 | Pistons | -3.5 | 215.5 | -162 | +136 | 107-97 DET |
| 5/5/2026 | Pistons | -3.5 | 216.5 | -158 | +133 | 111-101 DET |
| 3/3/2026 | Pistons | -2.5 | 228.5 | -147 | +122 | 113-109 CLE |
| 2/27/2026 | Pistons | -9 | 227.5 | -358 | +283 | 122-119 DET |
| 1/4/2026 | Cavaliers | -4.5 | 237.5 | -191 | +159 | 114-110 DET |
| 10/27/2025 | Cavaliers | -2.5 | 231.5 | -131 | +110 | 116-95 CLE |
| 3/28/2025 | Cavaliers | -6.5 | 233.5 | -273 | +221 | 133-122 DET |
| 2/5/2025 | Cavaliers | -3.5 | 234 | -159 | +135 | 118-115 CLE |
| 1/27/2025 | Cavaliers | -11 | 235 | -510 | +383 | 110-91 CLE |
| 10/25/2024 | Cavaliers | -10.5 | 225.5 | -581 | +425 | 113-101 CLE |
Cavaliers 2025-26 Betting Trends
- Cleveland is 34-47-1 against the spread this season.
- The Cavaliers are 18-32-1 against the spread when favored by 4.5 points or more this season.
- The teams have hit the over in 40 of Cleveland's 82 games with a set total.
- This season, the Cavaliers have been favored 66 times and won 45, or 68.2%, of those games.
- This season, Cleveland has won 37 of its 49 games, or 75.5%, when favored by at least -179 on the moneyline.
Pistons 2025-26 Betting Trends
- Detroit is 44-38-0 ATS this season.
- The Pistons have a 4-0 record against the spread this year when an underdog by 4.5 points or more.
- The teams have combined to hit the over in 38 of Detroit's 82 games with a set total.
- The Pistons are 12-3 in games they were the underdog on the moneyline (winning 80% of those games).
- In games it has played as a moneyline underdog with odds of +149 or longer, Detroit has gone 3-1 (75%).
Looking for NBA tickets? Head to StubHub today and see your team live.
Pistons vs. Cavaliers Injury Report
Cavaliers
Cavaliers: None
Pistons
Pistons:
Kevin Huerter: Questionable (Thigh),
Duncan Robinson: Questionable (Back),
Caris LeVert: Questionable (Heel)
Pistons vs. Cavaliers Game Time and TV Channel
- Game day: Friday, May 15, 2026
- Game time: 7 p.m. ET
- TV channel: Amazon Prime Video
- Location: Cleveland, Ohio
- Arena: Rocket Arena
Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason.