Donovan Mitchell and the Cleveland Cavaliers (23-19) are 2.5-point underdogs against Tyrese Maxey and the Philadelphia 76ers (22-17) Friday, January 16, 2026 at Xfinity Mobile Arena. The game tips off at 7 p.m. ET on ESPN, NBCS-PH, and FDSOH.
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Listen to the game on Newsradio WTAM 1100
76ers vs. Cavaliers Predictions for Friday
Our computer projection model for this matchup expects a final result of 76ers 119, Cavaliers 116.
- Moneyline Pick: 76ers (-148)
- Total Pick: Over 233.5 (computer predicts 235.0 points)
- Pick ATS: 76ers (-2.5)
Recent 76ers vs. Cavaliers Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 1/14/2026 | Cavaliers | -1.5 | 236.5 | -105 | -114 | 133-107 CLE |
| 11/5/2025 | Cavaliers | -10.5 | 235.5 | -483 | +368 | 132-121 CLE |
| 1/24/2025 | Cavaliers | -9.5 | 228.5 | -452 | +346 | 132-129 PHI |
| 12/21/2024 | Cavaliers | -10 | 221.5 | -442 | +343 | 126-99 CLE |
| 11/13/2024 | Cavaliers | -11 | 218 | -610 | +442 | 114-106 CLE |
76ers 2025-26 Betting Trends
- Philadelphia is 22-17-0 against the spread this season.
- The 76ers are 10-5 against the spread when favored by 2.5 points or more this season.
- In Philadelphia's 42 games with a set total, 21 have hit the over (50%).
- This season, the 76ers have won 17 out of the 24 games, or 70.8%, in which they've been favored.
- This season, Philadelphia has won 12 of its 14 games, or 85.7%, when favored by at least -148 on the moneyline.
Cavaliers 2025-26 Betting Trends
- So far this year, Cleveland has put together a 15-27-0 record against the spread.
- The Cavaliers are 3-2 against the spread when an underdog by 2.5 points or more this season.
- In Cleveland's 42 games with a set total, 20 have hit the over (47.6%).
- The Cavaliers have been the underdog on the moneyline eight total times this season. They've finished 3-5 in those games.
- When it has played as a moneyline underdog with odds of +124 or longer, Cleveland has a record of 2-1 (66.7%).
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76ers vs. Cavaliers Injury Report
76ers
76ers:
Dominick Barlow: Questionable (Back),
Joel Embiid: Probable (Knee),
Paul George: Probable (Knee)
Cavaliers
Cavaliers:
Max Strus: Out (Foot),
Dean Wade: Out (Knee),
Darius Garland: Out (Foot),
Sam Merrill: Out (Hand)
76ers vs. Cavaliers Game Time and TV Channel
- Game day: Friday, January 16, 2026
- Game time: 7 p.m. ET
- TV channel: ESPN, NBCS-PH, and FDSOH
- Location: Philadelphia, Pennsylvania
- Arena: Xfinity Mobile Arena
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
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