Cleveland Browns quarterback Shedeur Sanders has a difficult matchup in Week 16 (Sunday at 1 p.m. ET), playing the Buffalo Bills. The Bills are conceding the second-fewest passing yards in the league, 169.5 per game.
This season, Sanders has recorded passing 946 yards (189.2 per game), going 72-for-138 (52.2%) through the air with five touchdowns against six interceptions. Additionally, Sanders has rushed for 74 yards on the ground (14.8 per game) on 10 carries. Sanders also has one rushing touchdown.
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Sanders vs. the Bills
- Sanders vs the Bills (since 2021): No games
- Buffalo has not allowed an opposing quarterback to register 300 or more passing yards in an outing this year.
- Nine players have thrown one or more TDs in a game against the Bills this season.
- Five opposing quarterbacks have thrown for at least two TDs in a game against Buffalo in 2025.
- The Bills have allowed only one opposing player to throw for three or more TD passes in an outing this season.
- The 169.5 passing yards the Bills concede per contest makes them the second-ranked pass defense in the league this year.
- The Bills' defense is seventh in the NFL by conceding 1.1 passing touchdowns per game to opponents (16 total passing TDs).
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Sanders Passing Insights
- Sanders has gone over his passing yards total three times this year (75.0%).
- The Browns have passed 58.6% of the time and run 41.4% this season. They rank 29th in the NFL in scoring.
- Sanders has 946 yards on 138 attempts this season to average 6.9 yards per attempt.
- Sanders has completed at least one touchdown pass in three of five games, including multiple TDs once.
- He has scored six of his team's 23 offensive touchdowns this season (26.1%).
- Sanders has attempted eight passes in the red zone (8.2% of his team's red zone plays).
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Sanders' Recent Performance
| Opponent | Date | Week | Passing Stats | Rushing Stats |
|---|---|---|---|---|
| vs. Bears | 12/14/2025 | Week 15 | 18-for-35 / 177 YDS / 0 TDs / 3 INTs | 2 ATT / 24 YDS / 0 TDs |
| vs. Titans | 12/7/2025 | Week 14 | 23-for-42 / 364 YDS / 3 TDs / 1 INT | 3 ATT / 29 YDS / 1 TD |
| vs. 49ers | 11/30/2025 | Week 13 | 16-for-25 / 149 YDS / 1 TD / 0 INTs | 1 ATT / 6 YDS / 0 TDs |
| vs. Raiders | 11/23/2025 | Week 12 | 11-for-20 / 209 YDS / 1 TD / 1 INT | 1 ATT / -1 YDS / 0 TDs |
| vs. Ravens | 11/16/2025 | Week 11 | 4-for-16 / 47 YDS / 0 TDs / 1 INT | 3 ATT / 16 YDS / 0 TDs |