Bills vs. Browns Week 16 Predictions, Odds and Stats

Which team is going to win on Sunday, Dec. 21, when the Buffalo Bills and Cleveland Browns match up at 1 p.m. ET? Our projection system believes in the Bills. See our other projections below, where we break down the final score, spread, and over/under.

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Bills vs. Browns Game Info and TV Channel

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Bills vs. Browns Odds and Betting Info

  • Spread favorite: Bills (-10.5)
  • Moneyline: Bills (-625), Browns (+457)
  • Total: 40.5 points

Bills vs. Browns Prediction

  • Pick ATS: Bills (-10.5)
  • Pick OU: Over (40.5)

Prediction:

Bills 31 - Browns 15

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Bills vs. Browns Betting Insights

    • The Bills have won seven games against the spread this season, while failing to cover seven times.
    • The Browns have put together a 5-9-0 ATS record so far this season.
    • Buffalo has been favored by 10.5 points or more this season twice, and failed to cover both times.
    • Cleveland has not covered the spread when an underdog by 10.5 points or more this year (in one opportunity).
    • The Bills and their opponent have combined to hit the over seven out of 14 times this season.
    • The Browns and their opponent have combined to hit the over seven out of 14 times this year.

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