Shedeur Sanders Week 13 Preview vs. the 49ers

Shedeur Sanders will be facing the seventh-worst passing defense in the NFL when his Cleveland Browns meet the San Francisco 49ers in Week 13, on Sunday at 1 p.m. ET.

Sanders has racked up 256 passing yards (128.0 per game) this year, going 15-for-36 (41.7%) with one touchdown pass and two interceptions. Sanders has also contributed in the runnin game with 15 rushing yards (7.5 per game) on four attempts.

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Sanders vs. the 49ers

• Sanders vs the 49ers (since 2021): No games
• Three opposing players have registered 300 or more passing yards in an outing against San Francisco this year.
• The 49ers have allowed 11 players to throw one or more TDs in a game this season.
• San Francisco has allowed seven players to throw at least two touchdowns in a matchup in 2025.
• The 49ers have allowed three opposing players to throw for at least three TD passes in an outing this season.
• The 241.8 passing yards the 49ers give up per contest makes them the 26th-ranked pass defense in the league this year.
• Opponents of the 49ers have totaled 22 touchdowns through the air (1.8 per game). The 49ers' defense is 26th in the NFL in that category.

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Sanders Passing Insights

• The Browns, who are 29th in NFL play in points scored, have passed 58.1% of the time while running 41.9%.
• Sanders has averaged 7.1 yards per pass attempt this year.
• Sanders has thrown for a touchdown in one of two games this year, but has zero games with multiple passing TDs.
• He has one touchdown this season (5.6% of his team's 18 offensive TDs).

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Sanders' Recent Performance