A pair of hot teams square off when the Louisville Cardinals (4-0) visit the Cincinnati Bearcats (4-0) on November 21, 2025. The Cardinals will put their four-game win streak on the line against the Bearcats, who have won four straight.
The Cardinals play the Bearcats in a game that Louisville is currently a solid favorite by 9.5 points. The point total for the game is set at 162.5.
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Louisville vs. Cincinnati Odds and Game Info
- Game day: Friday, November 21, 2025
- Game time: 6:30 p.m. ET
- TV channel: ESPN2
- Location: Cincinnati, Ohio
- Arena: Heritage Bank Center
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Louisville vs. Cincinnati Odds and Prediction
- Spread favorite: Louisville (-9.5)
- Moneyline: Louisville (-490), Cincinnati (+369)
- Total: 162.5 points
Pick ATS:Cincinnati (+9.5)
- Pick OU: Under (162.5)
- Prediction: Louisville 79, Cincinnati 78
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Louisville vs. Cincinnati Comparison (2024-25 Stats)
| Louisville Rank | Louisville Stat | Cincinnati Stat | Cincinnati Rank | |
|---|---|---|---|---|
| 65th | 78.5 | Points Scored | 71.2 | 255th |
| 89th | 69.5 | Points Allowed | 66.2 | 33rd |
| 148th | 13.9 | Assists | 13.9 | 148th |
| 150th | 10.9 | Turnovers | 9.7 | 45th |
| 135th | 45.4% | Field Goal % | 44.9% | 162nd |
| 118th | 42.9% | Field Goal % Allowed | 43.1% | 128th |
Louisville 2024-25 Key Players
- Terrence Edwards averaged 16.7 points, 4.1 rebounds, and 2.7 assists per game last season.
- J'Vonne Hadley pulled down 7.3 rebounds per game, while Chucky Hepburn averaged 5.8 assists per contest.
- Reyne Smith hit an average of 3.5 shots per game from beyond the arc a season ago.
- Hepburn and James Scott were defensive standouts last season, with Hepburn averaging 2.4 steals per game and Scott collecting 0.8 blocks per contest.
Cincinnati 2024-25 Key Players
- Jizzle James scored 12.7 points and distributed 3.5 assists per game last season.
- Dillon Mitchell pulled down 6.8 rebounds per game while also scoring 9.9 points a contest.
- Simas Lukosius hit an average of 2.0 shots per game from beyond the arc a season ago.
- Day Day Thomas averaged 1.8 takeaways per game, while Aziz Bandaogo compiled 1.4 rejections per contest.
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